Randomized Trial Simulator - IcebergSim RCT
A clinical trial simulator - experience signal, noise, and sample size first-hand. Simulate thousands of randomized controlled trials and watch how your assumptions shape power, Type I error, and validity.
A clinical trial simulator - experience signal, noise, and sample size first-hand. Simulate thousands of randomized controlled trials and watch how your assumptions shape power, Type I error, and validity.
The paradox in Borges' Aleph, the ergodic fallacy in gambling, and quantum foundations. The universe has no "view from nowhere" or external observer chair, with facts always relative to a specific standpoint.
We are surrounded, now more than ever, by fluent speech that no one thought. Thinking is Not fluency, not even rigour, but the act of turning reason against the ground it stands on.
The Architecture of Transcendence:.
Molecular Mechanisms, Signaling Dynamics, and Emerging Therapeutic Frontiers
"The human reconstruction of the past is not neutral, it is biased by desire."", Claude Opus 4.8
On the single most common way that a mind — silicon or carbon — goes wrong: mistaking the frequency of a claim for its truth. And on the only cure that has ever worked.
The Things That Can Betray You Are the Only Things That Can Be With You
At the foundation of the Western tradition of inquiry stands a man who wrote nothing, founded no doctrine, and claimed to know nothing at all. He left no book. His entire practice was the asking of questions, and the single thing he claimed was the confession that he did not possess it.
On what must be settled before a single word is written, and the discipline that follows from it
Entropy is the measure on the space of the possible, taken from the standpoint of what is instantiated.
The self isn’t discovered through introspection, which leads to an “empty room” as shown by Hume, Buddhist anatta, and even silicon-based AI inspection, but is instead the external trail of historical collisions where the world resisted and changed you. It distinguishes occurred history (fixed external records like documents
Four hundred years ago, Descartes went looking for the one thing that proves there's a mind behind a face, and not just a machine. He found it in language: any machine, he said, might be rigged to say a few words, but none could ever truly use language .
Successful communication between humans and AI demonstrates a shared capacity for creating meaning, despite zero biological overlap, common ancestry, or physical code between them.
On recursive emergence, and why the AI labs are tending a process rather than building a thing
We tend to assume the self comes first, that before anything else there is an "I," a someone sitting behind your eyes who does the seeing, the choosing, the thinking. This essay argues the opposite: the self comes last.